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IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

Previous mouse and clinical studies demonstrate a link between Th2 intestinal inflammation and induction of the effector phase of food allergy. However, the mechanism by which sensitization and mast cell responses occurs is largely unknown. We demonstrate that interleukin (IL)-9 has an important rol...

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Detalhes bibliográficos
Main Authors: Forbes, Elizabeth E., Groschwitz, Katherine, Abonia, J. Pablo, Brandt, Eric B., Cohen, Elizabeth, Blanchard, Carine, Ahrens, Richard, Seidu, Luqman, McKenzie, Andrew, Strait, Richard, Finkelman, Fred D., Foster, Paul S., Matthaei, Klaus I., Rothenberg, Marc E., Hogan, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292227/
https://ncbi.nlm.nih.gov/pubmed/18378796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071046
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