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IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

Previous mouse and clinical studies demonstrate a link between Th2 intestinal inflammation and induction of the effector phase of food allergy. However, the mechanism by which sensitization and mast cell responses occurs is largely unknown. We demonstrate that interleukin (IL)-9 has an important rol...

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Bibliografiske detaljer
Main Authors: Forbes, Elizabeth E., Groschwitz, Katherine, Abonia, J. Pablo, Brandt, Eric B., Cohen, Elizabeth, Blanchard, Carine, Ahrens, Richard, Seidu, Luqman, McKenzie, Andrew, Strait, Richard, Finkelman, Fred D., Foster, Paul S., Matthaei, Klaus I., Rothenberg, Marc E., Hogan, Simon P.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292227/
https://ncbi.nlm.nih.gov/pubmed/18378796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071046
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