IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

Previous mouse and clinical studies demonstrate a link between Th2 intestinal inflammation and induction of the effector phase of food allergy. However, the mechanism by which sensitization and mast cell responses occurs is largely unknown. We demonstrate that interleukin (IL)-9 has an important rol...

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Hauptverfasser: Forbes, Elizabeth E., Groschwitz, Katherine, Abonia, J. Pablo, Brandt, Eric B., Cohen, Elizabeth, Blanchard, Carine, Ahrens, Richard, Seidu, Luqman, McKenzie, Andrew, Strait, Richard, Finkelman, Fred D., Foster, Paul S., Matthaei, Klaus I., Rothenberg, Marc E., Hogan, Simon P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292227/
https://ncbi.nlm.nih.gov/pubmed/18378796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071046
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