Disruption of c-Jun Reduces Cellular Migration and Invasion through Inhibition of c-Src and Hyperactivation of ROCK II Kinase

The spread of metastatic tumors to different organs is associated with poor prognosis. The metastatic process requires migration and cellular invasion. The protooncogene c-jun encodes the founding member of the activator protein-1 family and is required for cellular proliferation and DNA synthesis i...

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Hlavní autoři: Jiao, Xuanmao, Katiyar, Sanjay, Liu, Manran, Mueller, Susette C., Lisanti, Michael P., Li, Anping, Pestell, Timothy G., Wu, Kongming, Ju, Xiaoming, Li, Zhiping, Wagner, Erwin F., Takeya, Tatsuo, Wang, Chenguang, Pestell, Richard G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291431/
https://ncbi.nlm.nih.gov/pubmed/18216279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-08-0753
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