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Target concentration intervention is needed for tobramycin dosing in paediatric patients with cystic fibrosis – a population pharmacokinetic study

AIM: The primary aim was to estimate the population pharmacokinetic parameters of once-daily intravenous (i.v.) tobramycin in paediatric cystic fibrosis (CF) patients and to investigate the influence of covariates. The second aim was to assess the need for target concentration intervention (TCI) for...

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Hlavní autoři: Hennig, Stefanie, Norris, Ross, Kirkpatrick, Carl M J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291370/
https://ncbi.nlm.nih.gov/pubmed/17995972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03045.x
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