Sputum Tobramycin Concentrations in Cystic Fibrosis Patients with Repeated Administration of Inhaled Tobramycin

BACKGROUND: Dosing of tobramycin solution for inhalation (TSI) in cystic fibrosis (CF) patients was based on single-dose pharmacokinetic studies. This investigation was prompted by evidence of possible antibiotic accumulation in respiratory secretions with repeated dosing. The objectives were to eva...

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Библиографические подробности
Главные авторы: Ruddy, Jennifer, Emerson, Julia, Moss, Richard, Genatossio, Alan, McNamara, Sharon, Burns, Jane L., Anderson, Gail, Rosenfeld, Margaret
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2013
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621259/
https://ncbi.nlm.nih.gov/pubmed/22620494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2011.0942
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