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Bayesian Estimation of Tobramycin Exposure in Patients with Cystic Fibrosis
Fixed tobramycin (mg/kg) dosing is often inappropriate in patients with cystic fibrosis (CF), as pharmacokinetics are highly variable. The area under the concentration-time curve (AUC) is an exposure metric suited to monitoring in this population. Bayesian strategies to estimate AUC have been availa...
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| Publicado en: | Antimicrob Agents Chemother |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075075/ https://ncbi.nlm.nih.gov/pubmed/27572411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01131-16 |
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