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Population pharmacokinetics of high dose ibuprofen in cystic fibrosis

Methods: Blood samples were collected during routine clinical care; serum ibuprofen concentrations were determined by HPLC. Fitting of the concentration/time data to a one compartment kinetic population model was performed by a non-linear mixed effect regression method. Results: Body weight, dose, a...

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Detalhes bibliográficos
Main Authors: Arranz, I, Martin-Suarez, A, Lanao, J, Mora, F, Vazquez, C, Escribano, A, Juste, M, Mercader, J, Ripoll, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1719401/
https://ncbi.nlm.nih.gov/pubmed/14670788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/adc.88.12.1128
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