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Interaction between midazolam and clarithromycin in the elderly
AIM: To assess the relative contribution of intestinal and hepatic CYP3A inhibition to the interaction between the prototypic CYP3A substrate midazolam and clarithromycin in the elderly. METHODS: On day 1, 16 volunteers (eight male, eight female) aged 65–75 years weighing 59–112 kg received simultan...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291277/ https://ncbi.nlm.nih.gov/pubmed/17635500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02970.x |
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