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Pharmacokinetic interaction of riociguat with ketoconazole, clarithromycin, and midazolam
Abstract. Riociguat is a soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension that is principally metabolized via the cytochrome P450 (CYP) pathway. Three studies in healthy males investigated potential pharmacokinetic interactions between riociguat and CYP inhibitors (ke...
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| Publicado no: | Pulm Circ |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
University of Chicago Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860537/ https://ncbi.nlm.nih.gov/pubmed/27162627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685016 |
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