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Pharmacokinetic interaction of riociguat with ketoconazole, clarithromycin, and midazolam
Abstract. Riociguat is a soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension that is principally metabolized via the cytochrome P450 (CYP) pathway. Three studies in healthy males investigated potential pharmacokinetic interactions between riociguat and CYP inhibitors (ke...
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| Vydáno v: | Pulm Circ |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
University of Chicago Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860537/ https://ncbi.nlm.nih.gov/pubmed/27162627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685016 |
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