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Effects of omeprazole and aluminum hydroxide/magnesium hydroxide on riociguat absorption

Abstract. Riociguat, a soluble guanylate cyclase stimulator, is a novel therapy for the treatment of pulmonary hypertension. Riociguat bioavailability is reduced in neutral versus acidic conditions and therefore may be affected by concomitant use of medications that increase gastric pH. The effect o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pulm Circ
मुख्य लेखकों: Becker, Corina, Frey, Reiner, Unger, Sigrun, Artmeier-Brandt, Ulrike, Weimann, Gerrit, Mück, Wolfgang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: University of Chicago Press 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860530/
https://ncbi.nlm.nih.gov/pubmed/27162626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/682228
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