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Detecting evolutionary relationships across existing fold space, using sequence order-independent profile–profile alignments
Here, a scalable, accurate, reliable, and robust protein functional site comparison algorithm is presented. The key components of the algorithm consist of a reduced representation of the protein structure and a sequence order-independent profile–profile alignment (SOIPPA). We show that SOIPPA is abl...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291117/ https://ncbi.nlm.nih.gov/pubmed/18385384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704422105 |
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