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Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments

Computational methods for determining the secondary structure of RNA sequences from given alignments are currently either based on thermodynamic folding, compensatory base pair substitutions or both. However, there is currently no approach that combines both sources of information in a single optimi...

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Detalhes bibliográficos
Main Authors: Seemann, Stefan E., Gorodkin, Jan, Backofen, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582601/
https://ncbi.nlm.nih.gov/pubmed/18836192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn544
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