Hierarchical folding of multiple sequence alignments for the prediction of structures and RNA-RNA interactions

BACKGROUND: Many regulatory non-coding RNAs (ncRNAs) function through complementary binding with mRNAs or other ncRNAs, e.g., microRNAs, snoRNAs and bacterial sRNAs. Predicting these RNA interactions is essential for functional studies of putative ncRNAs or for the design of artificial RNAs. Many nc...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Seemann, Stefan E, Richter, Andreas S, Gorodkin, Jan, Backofen, Rolf
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903599/
https://ncbi.nlm.nih.gov/pubmed/20492641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-22
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