Hierarchical folding of multiple sequence alignments for the prediction of structures and RNA-RNA interactions

BACKGROUND: Many regulatory non-coding RNAs (ncRNAs) function through complementary binding with mRNAs or other ncRNAs, e.g., microRNAs, snoRNAs and bacterial sRNAs. Predicting these RNA interactions is essential for functional studies of putative ncRNAs or for the design of artificial RNAs. Many nc...

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Bibliographic Details
Main Authors: Seemann, Stefan E, Richter, Andreas S, Gorodkin, Jan, Backofen, Rolf
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903599/
https://ncbi.nlm.nih.gov/pubmed/20492641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-22
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