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Hierarchical folding of multiple sequence alignments for the prediction of structures and RNA-RNA interactions

BACKGROUND: Many regulatory non-coding RNAs (ncRNAs) function through complementary binding with mRNAs or other ncRNAs, e.g., microRNAs, snoRNAs and bacterial sRNAs. Predicting these RNA interactions is essential for functional studies of putative ncRNAs or for the design of artificial RNAs. Many nc...

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Detalhes bibliográficos
Main Authors: Seemann, Stefan E, Richter, Andreas S, Gorodkin, Jan, Backofen, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903599/
https://ncbi.nlm.nih.gov/pubmed/20492641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-22
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