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Analysis of optimal alignments unfolds aligners’ bias in existing variant profiles

Efforts such as International HapMap Project and 1000 Genomes Project resulted in a catalog of millions of single nucleotides and insertion/deletion (INDEL) variants of the human population. Viewed as a reference of existing variants, this resource commonly serves as a gold standard for studying and...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Tran, Quang, Gao, Shanshan, Phan, Vinhthuy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073887/
https://ncbi.nlm.nih.gov/pubmed/27766935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1216-1
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