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How genome complexity can explain the difficulty of aligning reads to genomes

BACKGROUND: Although it is frequently observed that aligning short reads to genomes becomes harder if they contain complex repeat patterns, there has not been much effort to quantify the relationship between complexity of genomes and difficulty of short-read alignment. Existing measures of sequence...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Phan, Vinhthuy, Gao, Shanshan, Tran, Quang, Vo, Nam S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674900/
https://ncbi.nlm.nih.gov/pubmed/26678826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S17-S3
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