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Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors

Activation of the cAMP/protein kinase A (PKA) second messenger cascade has been implicated in the induction of mechanical hyperalgesia by inflammatory mediators. We examined the role of this cascade in mechanical sensitization of nociceptive neurons that innervate the meninges, a process thought to...

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Detalhes bibliográficos
Main Authors: Levy, D, Strassman, A M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290080/
https://ncbi.nlm.nih.gov/pubmed/11790814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013175
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