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Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors

Activation of the cAMP/protein kinase A (PKA) second messenger cascade has been implicated in the induction of mechanical hyperalgesia by inflammatory mediators. We examined the role of this cascade in mechanical sensitization of nociceptive neurons that innervate the meninges, a process thought to...

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Détails bibliographiques
Auteurs principaux: Levy, D, Strassman, A M
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290080/
https://ncbi.nlm.nih.gov/pubmed/11790814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013175
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