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Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors
Activation of the cAMP/protein kinase A (PKA) second messenger cascade has been implicated in the induction of mechanical hyperalgesia by inflammatory mediators. We examined the role of this cascade in mechanical sensitization of nociceptive neurons that innervate the meninges, a process thought to...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290080/ https://ncbi.nlm.nih.gov/pubmed/11790814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013175 |
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