CYP4F2 genetic variant alters required warfarin dose

Warfarin is an effective, commonly prescribed anticoagulant used to treat and prevent thrombotic events. Because of historically high rates of drug-associated adverse events, warfarin remains underprescribed. Further, interindividual variability in therapeutic dose mandates frequent monitoring until...

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Bibliografische gegevens
Hoofdauteurs: Caldwell, Michael D., Awad, Tarif, Johnson, Julie A., Gage, Brian F., Falkowski, Mat, Gardina, Paul, Hubbard, Jason, Turpaz, Yaron, Langaee, Taimour Y., Eby, Charles, King, Cristi R., Brower, Amy, Schmelzer, John R., Glurich, Ingrid, Vidaillet, Humberto J., Yale, Steven H., Qi Zhang, Kai, Berg, Richard L., Burmester, James K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2008
Onderwerpen:
Hemostasis, Thrombosis, and Vascular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288721/
https://ncbi.nlm.nih.gov/pubmed/18250228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-122010
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