A Prospective, Randomized Pilot Trial of Model-Based Warfarin Dose Initiation using CYP2C9 Genotype and Clinical Data

Background: Rapid genetic screening for cytochrome P450 (CYP) 2C9 variants may play a role in improving the efficacy and safety of warfarin in individuals with CYP2C9 variants. The feasibility of prospective CYP2C9 model-based warfarin dosing has not yet been assessed. Objectives: To evaluate the fe...

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Hlavní autoři: Hillman, Michael A., Wilke, Russell A., Yale, Steven H., Vidaillet, Humberto J., Caldwell, Michael D., Glurich, Ingrid, Berg, Richard L., Schmelzer, John, Burmester, James K.
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2005. Clinical Medicine & Research 2005
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237155/
https://ncbi.nlm.nih.gov/pubmed/16160068
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