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Effects of Accessory Proteins on the Bypass of a cis-syn Thymine-Thymine Dimer by Saccharomyces cerevisiae DNA Polymerase η
Among several hypotheses to explain how translesion synthesis (TLS) by DNA polymerase η (pol η) suppresses ultraviolet light-induced mutagenesis in vivo despite the fact that pol η copies DNA with low fidelity, here we test whether replication accessory proteins enhance the fidelity of TLS by pol η....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2288658/ https://ncbi.nlm.nih.gov/pubmed/17608453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700234t |
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