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Pathway of ATP Hydrolysis by Monomeric Kinesin Eg5

Kinesin-5 family members including human Eg5/KSP contribute to the plus-end-directed force necessary for the assembly and maintenance of the bipolar mitotic spindle. We have used monomeric Eg5–367 in the nucleotide-free state to evaluate the role of microtubules at each step in the ATPase cycle. The...

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Detalhes bibliográficos
Main Authors: Cochran, Jared C., Krzysiak, Troy C., Gilbert, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288585/
https://ncbi.nlm.nih.gov/pubmed/17014086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0608562
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