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Mechanistic Analysis of the Mitotic Kinesin Eg5
Eg5 is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. We have analyzed two human Eg5/KSP motors, Eg5-367 and Eg5-437, and both are monomeric based on results from sedimentation velocity and...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2004
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356567/ https://ncbi.nlm.nih.gov/pubmed/15247293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M404203200 |
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