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Mechanistic Analysis of the Mitotic Kinesin Eg5

Eg5 is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. We have analyzed two human Eg5/KSP motors, Eg5-367 and Eg5-437, and both are monomeric based on results from sedimentation velocity and...

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Detalhes bibliográficos
Main Authors: Cochran, Jared C., Sontag, Christopher A., Maliga, Zoltan, Kapoor, Tarun M., Correia, John J., Gilbert, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356567/
https://ncbi.nlm.nih.gov/pubmed/15247293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M404203200
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