Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus

Animal toxins block voltage-dependent potassium channels (Kv) either by occluding the conduction pore (pore blockers) or by modifying the channel gating properties (gating modifiers). Gating modifiers of Kv channels bind to four equivalent extracellular sites near the S3 and S4 segments, close to th...

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Hlavní autoři: Chagot, Benjamin, Escoubas, Pierre, Villegas, Elba, Bernard, Cédric, Ferrat, Gilles, Corzo, Gerardo, Lazdunski, Michel, Darbon, Hervé
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286752/
https://ncbi.nlm.nih.gov/pubmed/15096626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03584304
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