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Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels

Acid-sensing ion channels (ASIC) are proton-gated sodium channels that have been implicated in pain transduction associated with acidosis in inflamed or ischemic tissues. APETx2, a peptide toxin effector of ASIC3, has been purified from an extract of the sea anemone Anthopleura elegantissima. APETx2...

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Detalhes bibliográficos
Main Authors: Chagot, Benjamin, Escoubas, Pierre, Diochot, Sylvie, Bernard, Cédric, Lazdunski, Michel, Darbon, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279311/
https://ncbi.nlm.nih.gov/pubmed/15987885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051378905
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