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Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels

Acid-sensing ion channels (ASICs) are thought to be important ion channels, particularly for the perception of pain. Some of them may also contribute to synaptic plasticity, learning, and memory. Psalmotoxin 1 (PcTx1), the first potent and specific blocker of the ASIC1a proton-sensing channel, has b...

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Detalhes bibliográficos
Main Authors: Escoubas, Pierre, Bernard, Cédric, Lambeau, Gérard, Lazdunski, Michel, Darbon, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323924/
https://ncbi.nlm.nih.gov/pubmed/12824480
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