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Structural stability and heat-induced conformational change of two complement inhibitors: C4b-binding protein and factor H

The complement inhibitors C4b-binding protein (C4BP) and factor H (FH) both consist of complement control protein (CCP) domains. Here we examined the secondary structure of both proteins by circular dichroism and Fourier-transform infrared technique at temperatures ranging from 30°C–90°C. We found t...

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Autors principals: Kask, Lena, Villoutreix, Bruno O., Steen, Mårten, Ramesh, Bala, Dahlbäck, Björn, Blom, Anna M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286748/
https://ncbi.nlm.nih.gov/pubmed/15075409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03516504
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