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Mapping of the Factor Xa Binding Site on Factor Va by Site-directed Mutagenesis
Activated coagulation factor V functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin. Based on the introduction of extra carbohydrate side chains in recombinant factor V, we recently proposed several regions in factor Va to be important for factor Xa binding. To further d...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258925/ https://ncbi.nlm.nih.gov/pubmed/18502757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802703200 |
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