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Analysis of Binding Sites on Complement Factor I That Are Required for Its Activity
The central complement inhibitor factor I (FI) degrades activated complement factors C4b and C3b in the presence of cofactors such as C4b-binding protein, factor H, complement receptor 1, and membrane cofactor protein. FI is a serine protease composed of two chains. The light chain comprises the ser...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825419/ https://ncbi.nlm.nih.gov/pubmed/20044478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097212 |
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