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Cooperativity in two-state protein folding kinetics

We present a solvable model that predicts the folding kinetics of two-state proteins from their native structures. The model is based on conditional chain entropies. It assumes that folding processes are dominated by small-loop closure events that can be inferred from native structures. For CI2, the...

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Detalles Bibliográficos
Autores principales: Weikl, Thomas R., Palassini, Matteo, Dill, Ken A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286727/
https://ncbi.nlm.nih.gov/pubmed/14978313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03403604
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