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Transition States in Protein Folding Kinetics: Modeling Φ-Values of Small β-Sheet Proteins()

Small single-domain proteins often exhibit only a single free-energy barrier, or transition state, between the denatured and the native state. The folding kinetics of these proteins is usually explored via mutational analysis. A central question is which structural information on the transition stat...

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Autore principale: Weikl, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186242/
https://ncbi.nlm.nih.gov/pubmed/17905840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109868
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