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Crystallographic identification of Ca(2+) and Sr(2+) coordination sites in synaptotagmin I C(2)B domain
Synaptotagmin I has two tandem Ca(2+)-binding C(2) domains, which are essential for fast synchronous synaptic transmission in the central nervous system. We have solved four crystal structures of the C(2)B domain, one of them in the cation-free form at 1.50 Å resolution, two in the Ca(2+)-bound form...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286539/ https://ncbi.nlm.nih.gov/pubmed/15340165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04832604 |
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