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Characterization of the Expression, Intracellular Localization, and Replication Complex Association of the Putative Mouse Hepatitis Virus RNA-Dependent RNA Polymerase

Mouse hepatitis virus (MHV) RNA synthesis is mediated by a viral RNA-dependent RNA polymerase (RdRp) on membrane-bound replication complexes in the host cell cytoplasm. However, it is not known how the putative MHV RdRp (Pol) is targeted to and retained on cellular membranes. In this report, we show...

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Autori principali: Brockway, Sarah M., Clay, Corrie T., Lu, Xiao Tao, Denison, Mark R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC228489/
https://ncbi.nlm.nih.gov/pubmed/12970436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10515-10527.2003
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