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Characterization of the Expression, Intracellular Localization, and Replication Complex Association of the Putative Mouse Hepatitis Virus RNA-Dependent RNA Polymerase

Mouse hepatitis virus (MHV) RNA synthesis is mediated by a viral RNA-dependent RNA polymerase (RdRp) on membrane-bound replication complexes in the host cell cytoplasm. However, it is not known how the putative MHV RdRp (Pol) is targeted to and retained on cellular membranes. In this report, we show...

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Detalhes bibliográficos
Main Authors: Brockway, Sarah M., Clay, Corrie T., Lu, Xiao Tao, Denison, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC228489/
https://ncbi.nlm.nih.gov/pubmed/12970436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10515-10527.2003
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