Cleavage between Replicase Proteins p28 and p65 of Mouse Hepatitis Virus Is Not Required for Virus Replication

The p28 and p65 proteins of mouse hepatitis virus (MHV) are the most amino-terminal protein domains of the replicase polyprotein. Cleavage between p28 and p65 has been shown to occur in vitro at cleavage site 1 (CS1), (247)Gly↓Val(248), in the polyprotein. Although critical residues for CS1 cleavage...

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Detalhes bibliográficos
Main Authors: Denison, Mark R., Yount, Boyd, Brockway, Sarah M., Graham, Rachel L., Sims, Amy C., Lu, XiaoTao, Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415798/
https://ncbi.nlm.nih.gov/pubmed/15140993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5957-5965.2004
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