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Cleavage between Replicase Proteins p28 and p65 of Mouse Hepatitis Virus Is Not Required for Virus Replication

The p28 and p65 proteins of mouse hepatitis virus (MHV) are the most amino-terminal protein domains of the replicase polyprotein. Cleavage between p28 and p65 has been shown to occur in vitro at cleavage site 1 (CS1), (247)Gly↓Val(248), in the polyprotein. Although critical residues for CS1 cleavage...

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Détails bibliographiques
Auteurs principaux: Denison, Mark R., Yount, Boyd, Brockway, Sarah M., Graham, Rachel L., Sims, Amy C., Lu, XiaoTao, Baric, Ralph S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC415798/
https://ncbi.nlm.nih.gov/pubmed/15140993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5957-5965.2004
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