Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism
Mammalian capping enzymes are bifunctional proteins with both RNA 5′-triphosphatase and guanylyltransferase activities. The N-terminal 237-aa triphosphatase domain contains (I/V)HCXXGXXR(S/T)G, a sequence corresponding to the conserved active-site motif in protein tyrosine phosphatases (PTPs). Analy...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12226 |
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