Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism

Mammalian capping enzymes are bifunctional proteins with both RNA 5′-triphosphatase and guanylyltransferase activities. The N-terminal 237-aa triphosphatase domain contains (I/V)HCXXGXXR(S/T)G, a sequence corresponding to the conserved active-site motif in protein tyrosine phosphatases (PTPs). Analy...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Wen, Yingxia, Yue, Zhenyu, Shatkin, Aaron J.
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 1998
Ngā marau:	Biological Sciences
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12226
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!