Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism

Mammalian capping enzymes are bifunctional proteins with both RNA 5′-triphosphatase and guanylyltransferase activities. The N-terminal 237-aa triphosphatase domain contains (I/V)HCXXGXXR(S/T)G, a sequence corresponding to the conserved active-site motif in protein tyrosine phosphatases (PTPs). Analy...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Wen, Yingxia, Yue, Zhenyu, Shatkin, Aaron J.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1998
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12226
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