Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

Mice, homozygous for disrupted ganglioside GM2/GD2 synthase (EC 2.4.1.94) gene and lacking all complex gangliosides, do not display any major neurologic abnormalities. Further examination of these mutant mice, however, revealed that the males were sterile and aspermatogenic. In the seminiferous tubu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Takamiya, Kogo, Yamamoto, Akihito, Furukawa, Keiko, Zhao, Jinmin, Fukumoto, Satoshi, Yamashiro, Shuji, Okada, Masahiko, Haraguchi, Masashi, Shin, Masashi, Kishikawa, Masao, Shiku, Hiroshi, Aizawa, Shinichi, Furukawa, Koichi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12147
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