Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

Mice, homozygous for disrupted ganglioside GM2/GD2 synthase (EC 2.4.1.94) gene and lacking all complex gangliosides, do not display any major neurologic abnormalities. Further examination of these mutant mice, however, revealed that the males were sterile and aspermatogenic. In the seminiferous tubu...

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Bibliografische gegevens
Hoofdauteurs: Takamiya, Kogo, Yamamoto, Akihito, Furukawa, Keiko, Zhao, Jinmin, Fukumoto, Satoshi, Yamashiro, Shuji, Okada, Masahiko, Haraguchi, Masashi, Shin, Masashi, Kishikawa, Masao, Shiku, Hiroshi, Aizawa, Shinichi, Furukawa, Koichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 1998
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22799/
https://ncbi.nlm.nih.gov/pubmed/9770454
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