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Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

Mice, homozygous for disrupted ganglioside GM2/GD2 synthase (EC 2.4.1.94) gene and lacking all complex gangliosides, do not display any major neurologic abnormalities. Further examination of these mutant mice, however, revealed that the males were sterile and aspermatogenic. In the seminiferous tubu...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Takamiya, Kogo, Yamamoto, Akihito, Furukawa, Keiko, Zhao, Jinmin, Fukumoto, Satoshi, Yamashiro, Shuji, Okada, Masahiko, Haraguchi, Masashi, Shin, Masashi, Kishikawa, Masao, Shiku, Hiroshi, Aizawa, Shinichi, Furukawa, Koichi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12147
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