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Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

Mice, homozygous for disrupted ganglioside GM2/GD2 synthase (EC 2.4.1.94) gene and lacking all complex gangliosides, do not display any major neurologic abnormalities. Further examination of these mutant mice, however, revealed that the males were sterile and aspermatogenic. In the seminiferous tubu...

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Detalhes bibliográficos
Main Authors: Takamiya, Kogo, Yamamoto, Akihito, Furukawa, Keiko, Zhao, Jinmin, Fukumoto, Satoshi, Yamashiro, Shuji, Okada, Masahiko, Haraguchi, Masashi, Shin, Masashi, Kishikawa, Masao, Shiku, Hiroshi, Aizawa, Shinichi, Furukawa, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22799/
https://ncbi.nlm.nih.gov/pubmed/9770454
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