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Insights into the DNA repair process by the formamidopyrimidine-DNA glycosylase investigated by molecular dynamics
Formamidopyrimidine-DNA glycosylase (Fpg) identifies and removes 8-oxoguanine from DNA. All of the X-ray structures of Fpg complexed to an abasic site containing DNA exhibit a common disordered region present in the C-terminal domain of the enzyme. However, this region is believed to be involved in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279820/ https://ncbi.nlm.nih.gov/pubmed/15273302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04772404 |
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