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Insights into the DNA repair process by the formamidopyrimidine-DNA glycosylase investigated by molecular dynamics

Formamidopyrimidine-DNA glycosylase (Fpg) identifies and removes 8-oxoguanine from DNA. All of the X-ray structures of Fpg complexed to an abasic site containing DNA exhibit a common disordered region present in the C-terminal domain of the enzyme. However, this region is believed to be involved in...

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Библиографические подробности
Главные авторы: Amara, Patricia, Serre, Laurence, Castaing, Bertrand, Thomas, Aline
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279820/
https://ncbi.nlm.nih.gov/pubmed/15273302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04772404
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