Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA

The formamidopyrimidine-DNA glycosylase (Fpg, MutM) is a bifunctional base excision repair enzyme (DNA glycosylase/AP lyase) that removes a wide range of oxidized purines, such as 8-oxoguanine and imidazole ring-opened purines, from oxidatively damaged DNA. The structure of a non-covalent complex be...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Serre, Laurence, Pereira de Jésus, Karine, Boiteux, Serge, Zelwer, Charles, Castaing, Bertrand
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126059/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065399/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf304
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