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Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA

The formamidopyrimidine-DNA glycosylase (Fpg, MutM) is a bifunctional base excision repair enzyme (DNA glycosylase/AP lyase) that removes a wide range of oxidized purines, such as 8-oxoguanine and imidazole ring-opened purines, from oxidatively damaged DNA. The structure of a non-covalent complex be...

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Autors principals: Serre, Laurence, Pereira de Jésus, Karine, Boiteux, Serge, Zelwer, Charles, Castaing, Bertrand
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC126059/
https://ncbi.nlm.nih.gov/pubmed/12065399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf304
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