Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments
Reassembly of enzymes from peptide fragments has been used as a strategy for understanding the evolution, folding, and role of individual subdomains in catalysis and regulation of activity. We demonstrate an oligomerization-assisted enzyme reassembly strategy whereby fragments are covalently linked...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12141 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|