How native-state topology affects the folding of dihydrofolate reductase and interleukin-1β
The overall structure of the transition-state and intermediate ensembles observed experimentally for dihydrofolate reductase and interleukin-1β can be obtained by using simplified models that have almost no energetic frustration. The predictive power of these models suggests that, even for these ver...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100547897 |
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