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How native-state topology affects the folding of dihydrofolate reductase and interleukin-1β
The overall structure of the transition-state and intermediate ensembles observed experimentally for dihydrofolate reductase and interleukin-1β can be obtained by using simplified models that have almost no energetic frustration. The predictive power of these models suggests that, even for these ver...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18526/ https://ncbi.nlm.nih.gov/pubmed/10811910 |
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