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How native-state topology affects the folding of dihydrofolate reductase and interleukin-1β

The overall structure of the transition-state and intermediate ensembles observed experimentally for dihydrofolate reductase and interleukin-1β can be obtained by using simplified models that have almost no energetic frustration. The predictive power of these models suggests that, even for these ver...

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Detalhes bibliográficos
Main Authors: Clementi, Cecilia, Jennings, Patricia A., Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18526/
https://ncbi.nlm.nih.gov/pubmed/10811910
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