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Generating somatic mosaicism with a Cre recombinase–microsatellite sequence transgene
Strategies for altering constitutional or somatic genotype in mice are well established, but approaches to generate mosaic genotypes in mouse tissues are limited. We showed that a functionally inactive Cre recombinase transgene with a long mononucleotide tract altering the reading frame was stochast...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279183/ https://ncbi.nlm.nih.gov/pubmed/18264107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/NMETH.1182 |
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