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Generating somatic mosaicism with a Cre recombinase–microsatellite sequence transgene

Strategies for altering constitutional or somatic genotype in mice are well established, but approaches to generate mosaic genotypes in mouse tissues are limited. We showed that a functionally inactive Cre recombinase transgene with a long mononucleotide tract altering the reading frame was stochast...

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Bibliografiska uppgifter
Huvudupphovsmän: Akyol, Aytekin, Hinoi, Takao, Feng, Ying, Bommer, Guido T, Glaser, Thomas M, Fearon, Eric R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279183/
https://ncbi.nlm.nih.gov/pubmed/18264107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/NMETH.1182
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